Histone deacetylase inhibitors could improve success rate of immunotherapy against lung cancer
A novel hybrid molecule synthesized and developed by a team at New York University (NY, USA) shows promise as a drug delivery mechanism with potential anti-cancer applications.
A collaborative team aim to investigate whether the ‘stressful’ conditions in space will stimulate drug-producing pathways in fungus
Pharmacologically active plant-derived natural products: challenges and opportunities in drug discovery
A team of researchers co-led by our MedChemNet Leader Atanas Atanasov (University of Vienna, Austria) have prepared a comprehensive review of the latest advances in natural product-derived drug discovery, giving important insights into the future of the field.
Researchers from the University of California, Los Angeles (CA, USA) and Shanghai Jiao Tong University (Shanghai, China) have utilized a novel technique to study the potential of different drug combinations as faster and more effective treatment options for tuberculosis.
A team from the University of Minnesota (MN, USA) has made strides towards developing an oral contraceptive for men by making small changes to promising experimental compounds.
An international team has developed a novel therapeutic compound effective in inhibiting the most deadly species of malaria-causing parasite.
Researchers co-led by scientists from the University of Kent (Canterbury, UK) and Goethe University (Frankfurt, Germany) have identified a first step in the design of a new generation of anti-cancer therapeutics.
Researchers from the University of Toronto Faculty of Applied Science & Engineering (Canada) have developed a novel way to grow realistic human tissue outside the body, providing a powerful new platform for drug discovery and testing, and with potential applications for eventual repair or replacement of damaged organs.
Spotlight on computer-aided drug design, Computational chemistry and informatics, News, Technologies and methodologies
Researchers at Lawrence Livermore National Laboratory (CA, USA) are using supercomputers to form simulations potentially able to significantly speed up the process of candidate drug testing.
Researchers from the Walter and Eliza Hall Institute (Victoria, Australia) have discovered that the best treatment for the most deadly form of blood cancer may be to combine two recently developed drugs.
A team from the Walter and Eliza Hall Institute (Melbourne, Australia) have resolved a mystery about the action of a novel class of anti-cancer drugs, nutlins, with potential implications for future cancer treatments.
Jack Scannell from Oxford University's Centre for the Advancement of Sustainable Medical Innovation (UK) and consultant Jim Bosley have used mathematical tools to address the hypothesis that poor choices of study method are the root of unsustainably expensive drug discovery.
A team from the Johns Hopkins Bloomberg School of Public Health (MD, USA) has developed tiny brain-like structures, made up of human neurons and cells, with the potential to dramatically change how drugs for neurological conditions are evaluated.
Spotlight on computer-aided drug design, Computational chemistry and informatics, Drug discovery approaches, Drug regulation and industry, News
Researchers from Carnegie Mellon University (PA, USA) have created the first robotics-driven system to determine the effects of drugs on proteins, drastically reducing the number of necessary experiments.