Patent highlights: December 2017–January 2018
In this article, brought to MedChemNet users by Pharmaceutical Patent Analyst, Hermann Mucke provides a snapshot of noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development.
Hermann AM Mucke1
1HM Pharma Consultancy, A-1160, Wien, Austria
Noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development, set to be published in Volume 7 Issue 3 of Pharmaceutical Patent Analyst. The full article is available to view here.
December
January
WO/2017/207600
New treatment of SMA
Inventors: Blättler T, McCarthy KD, Sanwald Ducray P & Schädeli Stark
Assignee: F Hoffmann-LaRoche AG (Basel, Switzerland)
MeSH keywords: neuroprotective agents; spinal muscular atrophy
Published: 7 December 2017
WO/2017/210523
KLRG1 signaling therapy
Inventors: Greenberg S, Gulla SV & Thompson KE
Assignee: The Brigham & Women's Hospital, Boston (MA, USA)
MeSH keywords: lectins, C-type; melanoma; receptors, immunologic
Published: 7 December 2017
WO/2017/214579
Compositions & methods for treating osteoporosis
Inventors: Pilz R, Boss G & Kalyamaraman H
Assignee: The Regents of the University of California, Oakland (CA, USA)
MeSH keywords: cobamides; isosorbide mononitrate; osteoporosis
Published: 14 December 2017
WO/2017/216792
PERK inhibitors & uses thereof in treating diseases associated with aggregation-prone proteins
Inventors: Lederkremer GZ, Leitman J, Eiger H, Offen D, Ganz J & Portinoy M
Assignee: Ramot at Tel-Aviv University Ltd (Tel Aviv, Israel)
MeSH keywords: basal ganglia; endoplasmic reticulum stress; Huntington's disease
Published: 21 December 2017
WO/2017/217935
Use of miR-198 in treating & diagnosing cutaneous squamous cell carcinoma
Inventors: Sampath P, Gopinath S & Quah S
Assignee: Agency for Science, Technology & Research (Singapore)
MeSH keywords: follistatin-related proteins; miR-198, human; skin neoplasms; squamous cell carcinoma
Published: 21 December 2017
WO/2017/222713
A GPR119-based signaling system in the murine eye regulates intraocular pressure in a sex-dependent manner
Inventors: Straiker A
Assignee: Indiana University Research & Technology Corp., Indianapolis (IN, USA)
MeSH keywords: 2-oleyl glycerol ether; G-protein-coupled receptor 119; glaucoma
Published: 28 December 2017
WO/2017/223260
PU.1 inhibitors
Inventors: Wilson WD, Boykin DW, Poon G, Steidl U & Anthony-Debré I
Assignee: Albert Einstein College of Medicine, Inc., Atlanta (GA, USA); Georgia State University Research Foundation, Inc., Atlanta (GA, USA)
MeSH keywords: acute myeloid leukemia; acute promyelocytic leukemia; proto-oncogene proteins
Published: 28 December 2017
WO/2018/001565
Use of Lyso-GB1 as a druggable target
Inventors: Cozma C & Bauer P
Assignee: Centogene AG (Rostock, Germany)
MeSH keywords: animal model; Gaucher disease; glucosylsphingosine
Published: 4 January 2018
WO/2018/001666
Modulators of vault RNAs for use in the treatment of diseases
Inventors: Horos R, Hentze M & Sachse C
Assignee: European Molecular Biology Laboratory (Heidelberg, Germany)
MeSH keywords: autophagy; sequestosome-1 protein; vault ribonucleoprotein particle
Published: 4 January 2018
WO/2018/005812
A new & potent class of TLR agonists
Inventors: Beutler B & Boger DL
Assignee: The Scripps Research Institute, La Jolla (CA, USA); The Board of Regents of the University of Texas System, Austin (TX, USA)
MeSH keywords: infection; stereoisomerism; toll-like receptors
Published: 4 January 2018
WO/2018/007801
A probe for targeting & manipulating mitochondrial function using quantum dots
Inventors: Naasani I
Assignee: Nanoco Technologies Ltd (Manchester, UK)
MeSH keywords: mitochondria; quantum dots
Published: 11 January 2018
WO/2018/010856
HRI activators useful for the treatment of cardiometabolic diseases
Inventors: Zarei M, Vázquez Carrera M, Vázquez Cruz S, Leiva Martínez R & Pujol Bech E
Assignee: Universitat de Barcelona (Barcelona, Spain)
MeSH keywords: eIF-2 kinase; fibroblast growth factors; metabolic syndrome
Published: 18 January 2018
WO/2018/013930
Mechanical opening of lipid bilayers by molecular nanomachines
Inventors: Tour JM, Pal R, Garcia V & Nilewski L
Assignee: William Marsh Rice University, Houston (TX, USA)
MeSH keywords: drug delivery
Published: 18 January 2018
WO/2018/017888
Multimeric OX40 binding molecules & uses thereof
Inventors: Wang Bt-Y, Rosner DR, Baliga R & Keyt BA
Assignee: IGM Biosciences, Inc., Mountain View (CA, USA)
MeSH keywords: cellular immunity; OX40 receptor; recombinant proteins
Published: 25 January 2018
Source: Mucke HAM. Patent highlights from December 2017 to January 2018. Pharmaceutical Patent Analyst. 7(3), 111-119 (2018)
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