Patent highlights: April–May 2018

In this article, brought to MedChemNet users by Pharmaceutical Patent Analyst, Hermann Mucke provides a snapshot of noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development.

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Sep 24, 2018
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Hermann AM Mucke1
1HM Pharma Consultancy, A-1160, Wien, Austria

Noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development, set to be published in Volume 7 Issue 5 of Pharmaceutical Patent Analyst. The full article is available to view here.

April

May

WO/2018/058246

Treatment of inflammatory bowel disease with nucleoside triphosphate diphosphohydrolase, P2Y2 antagonist &/or P2Y6 antagonist

Inventors: Sévigny J, Salem M

Assignee: Université Laval (Québec, Canada)

MeSH keywords: adenosine triphosphatases/colitis; purinergic P2; ulcerative/receptors

Published: 5 April 2018

WO/2018/059263

Bismuth (III) compounds & methods thereof

Inventors: Sun H, Kao RYT, Wang R, Lai TP, Zhang H, Li H

Assignee: The University of Hong Kong (Hong Kong, China)

MeSH keywords: β-lactamase NDM-1; β-lactam resistance; bismuth subcitrate

Published: 5 April 2018

WO/2018/067638

HMGB1 protein inhibitors

Inventors: Kovacs B, Shahbahrami K, Nicola G

Assignee: Afecta Pharmaceuticals, Inc. (CA, USA)

MeSH keywords: HMGB1 protein; interleukins

Published: 12 April 2018

WO/2018/070510

Myogenesis-inducing agent

Inventors: Hohjoh H, Fukuoka M

Assignee: National Center of Neurology and Psychiatry (Tokyo, Japan)

MeSH keywords: miR-199a, human; muscular atrophy; muscular dystrophies

Published: 19 April 2018

WO/2018/071531

Methods of treating diseases associated with repeat instability

Inventors: Pearson CE, Nakamori M, Nakatani K

Assignee: The Hospital for Sick Children (Toronto, Canada); Osaka University (Osaka, Japan)

MeSH keywords: genomic instability; Huntington disease; trinucleotide repeat expansion

Published: 15 February 2018

WO/2018/031579

HPPK inhibitors useful as antibacterial agents

Inventors: Ji X, Genbin S, Shaw GX

Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services (MD, USA)

MeSH keywords: antibacterial agents; diphosphotransferases

Published: 19 April 2018

WO/2018/073474

Allosteric TAO inhibitors as antiparasitical & antifungal agents

Inventors: Dardonville C, De Koning HP, Ebiloma GU

Assignee: Consejo Superior de Investigaciones Científicas (Madrid, Spain); The University Court of the University of Glasgow (UK)

MeSH keywords: antifungal agents; oxidoreductases; trypanocidal agents; trypanosomiasis

Published: 26 April 2018

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WO/2018/081085

Methods of diagnosis & treatment of Alzheimer's disease

Inventors: Zhan X, Stamova B, Sharp F

Assignee: The Regents of the University of California (CA, USA)

MeSH keywords: Alzheimer disease; Escherichia coli; lipopolysaccharides

Published: 3 May 2018

WO/2018/083157

Substituted pyrido[3,4-b]indoles for the treatment of cartilage disorders

Inventors: Gretzke D, Ritzeler O, Heinelt U, Wehner V, Schmidt F

Assignee: Sanofi SA (Paris, France)

MeSH keywords: carbolines; osteoarthritis; SOX transcription factors

Published: 11 May 2018

WO/2018/085491

5-HT1F receptor agonists & mitochondrial biogenesis

Inventors: Lindsey CC, Beeson CC, Schnellmann RG

Assignee: MUSC Foundation for Research Development (SC, USA); US Department of Veterans Affairs (DC, USA)

MeSH keywords: acute kidney injury; serotonin 1F receptor

Published: 11 May 2018

WO/2018/086530

Sulfonamide compound as cccDNA inhibitor

Inventors: Fu Z, Zhang Y, Luo M, Chen S, Li J, Xu H, Yang L, Zhang X

Assignee: Chia Tai Tianqing Pharmaceutical Group Co. Ltd (Jiangsu, China)

MeSH keywords: circular DNAs; hepatitis B, chronic

Published: 17 May 2018

WO/2018/091598

Treatment of neurodegenerative diseases

Inventors: Guerreiro da Silva S, Michel PP

Assignee: Institut du Cerveau et de la Moelle Epinière (Paris, France); Université Pierre et Marie Curie (Paris, France); Centre National de la Recherche Scientifique (Paris; France); Institut National de la Santé et de la Recherche Médicale (Paris, France)

MeSH keywords: Alzheimer disease; calcium channels; NAADP; TPC1 protein, human; Parkinson disease; TPC2 protein, human

Published: 24 May 2018

WO/2018/095877

Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions & uses thereof

Inventors: Eckhardt M, Peters S, Wagner H

Assignee: Boehringer Ingelheim International GmbH (Ingelheim am Rhein, Germany)

MeSH keywords: diabetes mellitus; FFAR1 protein, human

Published: 31 May 2018

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Source: Mucke HAM. Patent highlights April–May 2018Pharmaceutical Patent Analyst. (Ahead of print) doi:10.4155/ppa-2018-0022 (2018) 

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Hermann Mucke

CEO, H.M. Pharma Consultancy

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